- By Shelley Frost
- February 21, 2025
- Polynucleotides, Skin Boosters, Skin Rejuvenation
- Comments:1
Under eye polynucleotides are an injectable treatment that stimulates collagen and elastin production in the delicate under-eye area, gradually improving dark circles, hollows, fine lines and skin laxity. Unlike tear trough filler, they add no volume, making them the safer option for patients who are not suitable candidates for filler or who want a more natural, long-term result.
Nurse-led in Wigan · Shelley Frost, prescriber
Under-eye polynucleotides
From £250
Refreshed, natural under-eyes using regulated products, with honest advice from a nurse prescriber.
What are Under Eye Polynucleotides, and Why Choose Them over Traditional Fillers?
At SF Aesthetics in Wigan, more clients want non-surgical and natural cosmetic procedures instead of dermal fillers. We now have a new treatment in clinic under eye Polynucleotide treatment! The injectable treatment of polynucleotides under eyes is a more natural eye rejuvenation.
This is also safer alternative to risky tear trough filler to treat hollowing under the eyes. I often tell patients in my Wigan clinic that they may not be good candidates for tear trough filler. This is because of the risk of complications.
The delicate under eye area is thin and delicate. This makes it more likely to age, loose skin laxity, and eye hollowing. The loss of natural collagen in your skin contributes to these issues.
Polynucleotides injected under the eyes help skin rejuvenation for the long term. They stimulate collagen production for months after treatment ends. This eye injectable treatment safely reduces under-eye bags and hollows.
Under Eye Polynucleotide Treatment
Polynucleotides target these concerns at the cellular level, this boosts the under-eye area. The polynucleotide benefits include:
- Improving poor skin tone,
- fine lines,
- wrinkles
- dark circles
| Treatment | Sessions | Price |
|---|---|---|
| Under Eye Polynucleotides | Single session | From £250 |
| Under Eye Polynucleotides | Course of 3 Recommended |
From £700 |
Polynucleotide Under Eyes Benefits
Many clients in Wigan want polynucleotide treatments. These treatments help refresh their under-eye area. They do this without adding puffy volume like fillers do.
Polynucleotide filler works like a skin booster. It has many benefits for treating the under-eye area. Here are some of them:
- Increased collagen and elastin production for long-term skin health.
- Hydrated and firm skin to reduce puffiness and dark circles.
- Smoother fine lines and wrinkles like crow’s feet without adding unnatural volume.
- Minimised appearance of hollow and tired under eyes, offering a refreshed and youthful look.
Polynucleotides vs Tear Trough Filler — What Is the Difference?
Immediate vs. Gradual Results:
Both treatments address the under-eye area, but they work completely differently and suit different patients.
Tear trough filler – uses hyaluronic acid to add volume instantly, correcting hollowness and improving the appearance of dark circles caused by shadowing. Results are immediate but carry risks specific to the under-eye area, including the Tyndall effect (a blue-grey discolouration), swelling and, in rare cases, vascular complications. Shelley assesses every patient carefully before recommending filler for this area.
Under eye polynucleotides add no volume whatsoever. Instead they trigger the skin to produce its own collagen and elastin over a period of weeks and months. Results are gradual but deeply natural, and the risk profile is significantly lower than filler in this sensitive area.
What Can Under Eye Polynucleotides Treat?
- Dark circles caused by skin thinning and loss of collagen
- Fine lines and crepe-like texture in the under-eye area
- Mild hollowing and tiredness
- Skin laxity and poor skin quality in the periorbital area
- Patients who are not suitable candidates for tear trough filler
- Post-filler skin quality improvement
Longevity of Results:
- Tear trough fillers last 6-12 months. Often require repeat treatments each time holding risk of complications.
- Polynucleotides under eyes effects can last longer as they improve the skin from within. Although the results can be a slow burner, the long term effects are more natural and a safer treatment with less complications.
What Is Each Treatment Best For?
- Tear trough fillers are ideal for instant volume correction
- Polynucleotides are better suited for long-term skin health and rejuvenation.
What to Expect at Your Under Eye Polynucleotide Treatment
Consultation Shelley will assess your under-eye area carefully — looking at skin thickness, degree of hollowing, the presence of veins and whether your concerns are better suited to polynucleotides or filler. There is no pressure to proceed with any treatment at the consultation.
The treatment A topical numbing cream is applied before the injections. Polynucleotides are administered using a very fine needle into the under-eye skin. The procedure takes approximately 20 to 30 minutes. Most patients describe mild discomfort — nothing more.
After treatment Some swelling and redness at the injection sites is completely normal and typically resolves within 24 to 48 hours. Mild bruising can occur. You can return to normal activities immediately — avoid makeup for six hours.
When you will see results The collagen stimulation process begins immediately but visible improvement takes time. Most patients notice the first changes at four to six weeks after their first session. Full results are visible after completing a course of two to three sessions.
Polynucleotide Under Eyes Reviews
Some of my recent results in clinic following treatment of under eye ageing with polynucleotides.
Why Choose Under Eye Polynucleotide Treatment Over Other Treatments?
- Non-Volumising, Natural Look: Unlike fillers that make the skin fuller, polynucleotides focus on rejuvenation. They help renew the skin and give more natural results.
- Long-Term Benefits: It boosts collagen, elastin, and hydration. This makes it great for patients seeking lasting improvements instead of quick fixes.
- Minimal Downtime and Low Risk: Polynucleotide injections are less invasive than surgery or other treatments. They have fewer side effects.
Why Wigan Clients Love Polynucleotides Eye Treatment
Polynucleotide treatment in Wigan has become one of our most popular treatments in our clinic. This is because it offers a safe and effective way to refresh the undereye area. This is for my Wigan patients who were told that tear trough filler is not an option.
Have you previously been to our Wigan clinic and told that tear trough filler was just not an option for your under eye? Alternatively have you had a complication with swelling after tear trough filler in the past?
Well now there is an alternative in polynucleotide under eyes treatment to rejuvenate your eye area.
Shelley at SF Aesthetics in Wigan, Greater Manchester, has over 10 years of experience. She offers safe and natural results to clients in Wigan, Standish, Leigh, and the Greater Manchester area.
Ready to take your first step in achieving a brighter, younger under eye safely?
Visit us in Wigan to explore if polynucleotides are right for you
Polynucleotide Eye Treatment FAQ
Is polynucleotide good for under eyes?
Yes, polynucleotides are one of the most effective treatments available specifically for the under-eye area. They stimulate collagen and elastin production in the thin, delicate skin around the eyes, gradually improving dark circles, fine lines, skin laxity and hollowness. Unlike tear trough filler, they carry a very low risk of complications, making them suitable for patients who cannot safely have filler in this are
How long do polynucleotides stay under the eyes?
The effects of under eye polynucleotide treatment typically last six to twelve months after completing a course of two to three sessions. Because the treatment works by stimulating your own collagen production, results continue to improve for several months after the course ends. Annual maintenance sessions help sustain results over the long term.
Can anything go wrong with polynucleotides?
Polynucleotides are considered a very safe treatment with a low risk of complications. The most common side effects are temporary, mild swelling, redness and small raised blebs at the injection sites, which typically settle within 24 to 72 hours. Rare complications include prolonged swelling or bruising. Choosing a qualified and experienced practitioner like Shelley Frost at SF Aesthetics significantly reduces the risk of any adverse effects.
Are polynucleotides better than fillers?
This depends on your specific concern and what you want to achieve. Polynucleotides are better for improving overall skin quality, reducing dark circles caused by skin thinning and stimulating long-term collagen — with a lower risk profile than filler in the under-eye area. Tear trough filler is better for instant volume correction in patients with significant hollowing who are suitable candidates. Shelley will assess your under-eye area at your consultation and give you an honest recommendation.
Is one session of polynucleotides enough?
For most patients, one session alone will not deliver the full result. A course of two to three sessions spaced two to four weeks apart is recommended to allow the collagen stimulation to build progressively. Some improvement may be visible after the first session, but the optimal result is achieved after completing the full course. Maintenance sessions every 12 months help sustain results.
Do polynucleotides look worse before better?
Some patients notice mild swelling or small raised areas at the injection sites in the first 24 to 72 hours after treatment, this is completely normal and part of the healing process. The under-eye area may temporarily look slightly puffy before it settles. Results then begin to improve gradually from four weeks onwards as collagen production increases. This is not a treatment for instant results – patience is important.
How long do polynucleotides take to work under eyes?
Most patients begin to notice visible improvement four to six weeks after their first session. Full results are visible after completing a course of two to three sessions and continue to improve for several months afterwards as collagen continues to build. The gradual nature of the results is what makes them look so natural.
Do polynucleotides work under eyes?
Yes, polynucleotides are clinically proven to stimulate collagen and elastin production, improve skin hydration and reduce the appearance of dark circles and fine lines in the under-eye area. Results vary depending on the degree of the concern being treated and individual factors such as skin thickness and age. Shelley will give you an honest assessment of what polynucleotides can realistically achieve for your specific under-eye concerns at your consultation.
Are polynucleotides safe under eyes?
Yes — when administered by a qualified and experienced practitioner. Polynucleotides are made from purified DNA fragments which are biocompatible and biodegradable. They cannot cause vascular occlusion, one of the most serious risks associated with hyaluronic acid fillers in the under-eye area – making them a significantly safer alternative for this delicate zone. At SF Aesthetics, all injectable treatments are administered by Shelley Frost, a qualified nurse prescriber.
How often should you get polynucleotides under eyes?
A course of two to three sessions spaced two to four weeks apart is the standard recommendation. After completing the initial course, most patients return for a single maintenance session every 12 months. Shelley will advise on the right frequency for your skin at your consultation.
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